yy1a YY1 transcription factor a [Danio rerio (zebrafish)] - Gene (2024)

FAQs

How many genes does Danio Rerio have? ›

p. 499 left column 3rd paragraph: "Zebrafish possess 26,206 protein-coding genes [ref 6], more than any previously sequenced vertebrate, and they have a higher number of species-specific genes in their genome than do human, mouse or chicken.

Transcription Factor yin-Yang 1 augments nucleoporin 93 oncogene activity and modulates bladder Cancer malignancy. YY1 is involved in hom*ologous recombination inhibition at guanine quadruplex sites in human cells. YY1/circCTNNB1/miR-186-5p/YY1 positive loop aggravates lung cancer progression through the Wnt pathway.

However, the motifs for only 10% of the estimated 763 transcription factors in C. elegans have been identified so far. In this study, Narasimhan, Lambert, Yang et al. used a technique called a 'protein binding microarray' to identify the motifs for many more of the C.

Although the number of genes for the transcription factors in mammals lies around 1600, the total number of functional factors is much higher as many of those factors have multiple isoforms arising out of alternative splicing.

In the last 20 years, the zebrafish Danio rerio has become well-established as a model organism, particularly for the study of the genetics of early vertebrate development.

And, it turns out; the fish are a lot like people. Humans and zebrafish share 70 percent of the same genes and 84 percent of human genes known to be associated with human disease have a counterpart in zebrafish.

Yin Release is the manipulation of a shinobi's spiritual energy, and Yang Release is the manipulation of a shinobi's life energy. When combined together, both form Yin-Yang Release, the rarest and most powerful nature transformation in the series.

Definition. The principle of Yin and Yang from Chinese philosophy is that all things exist as inseparable and contradictory opposites. Examples of Yin-Yang opposite forces are female-male, dark-light, and old-young. The pairs of equal opposites both attract and complement each other.

The DNA-binding domain of YY1 is composed of four C₂H₂ zinc fingers. Threonine 348 is located between zinc fingers 2 and 3, and threonine 378 is located between zinc fingers 3 and 4. A closer examination of these two sites revealed that they are part of a consensus linker peptide sequence.

elegans is one of the most intimately understood species in biology—the first animal to have its complete genome sequenced or its neural circuitry completely mapped.

How do you identify transcription factors of a gene? ›

The ChIP assay is a very powerful technique used to identify regions of a genome associated with specific proteins including but not limited to transcription factors within their native chromatin context (1). In this technique, intact cells are fixed with formaldehyde to cross-link proteins with their associated DNA.

On average, the amino acid similarity and identity between aligned human and C. elegans orthologous gene products are 69.3% and 49.1% respectively, and the nucleotide identity is 49.8%.

Therefore, approximately 10% of genes in the genome code for transcription factors, which makes this family the single largest family of human proteins.

Transcription factors are vital molecules in the control of gene expression, directly controling when, where and the degree to which genes are expressed. They bind to specific sequences of DNA and control the transcription of DNA into mRNA.

Transcription factors are proteins involved in the process of converting, or transcribing, DNA into RNA. Transcription factors include a wide number of proteins, excluding RNA polymerase, that initiate and regulate the transcription of genes.

Despite the apparent differences between humans and zebrafish, these freshwater fish share 70% of human genes. This similarity extends to various organs and biological processes, making zebrafish a viable model for studying diseases affecting humans. Zebrafish embryos are laid externally and can be manipulated.

Although humans may appear to be extremely different than zebrafish, we are actually much more similar to them than you might think. In fact, 70% of human genes are found in zebrafish .

The lungfish genome contains 17,095 ncRNA genes, including 1,042 tRNA genes, 1,771 rRNA genes, and 3,974 microRNA genes.